Saie is a clean makeup brand known for its high-performance, skin-enhancing essentials. They prioritize safe, potent ingredients derived from nature and supported by science, alongside a strong commitment to sustainable practices. This includes using recyclable glass packaging, 100% recycled FSC-certified paper for cartons. Saie is also recognized for its innovative formulas that create a dewy, "no-makeup makeup" look, and for being vegan and cruelty-free.

Sand & Sky is an Australian skincare brand celebrated for harnessing native botanicals like pink clay and Australian emu apple. Known for its Australian Pink Clay Porefining Face Mask, the brand focuses on detoxifying and brightening results. It's cruelty-free, clean-leaning, and committed to minimal, effective routines.

Saturday Skin is a K-beauty inspired brand promoting a healthy, youthful glow with natural extracts and peptides. They uphold a "clean beauty promise," are vegan and cruelty-free, and their Waterfall Glacier Water Cream is notable for lightweight hydration.

Sephora Collection is Sephora's affordable in-house brand, offering a wide range of trendy and accessible makeup, skincare, and tools. It's known for its broad appeal and participation in the "Clean at Sephora" program, ensuring formulations free from certain undesirable ingredients. Consumers appreciate its value and ability to stay current with beauty trends.

Shani Darden Skincare is a results-driven luxury skincare brand founded by celebrity esthetician Shani Darden, known for its effective and simple formulations. Her unique offering is bringing professional-grade treatments and products, like the Retinol Reform and Facial Sculpting Wand, to at-home users. Generally considered clean and vegan, consumers trust the brand for visible skin improvements.

Shiseido, a renowned Japanese beauty conglomerate with a rich history, is celebrated for its advanced skincare technology, luxurious textures, and innovative makeup. While not a "clean beauty" brand by Western definitions, they uphold rigorous Japanese quality and safety standards and demonstrate a strong commitment to sustainability through responsible sourcing, environmental impact reduction, and social initiatives. Their Ultimune Power Infusing Concentrate and Benefiance Wrinkle Smoothing Cream are iconic, leading consumers to widely regard Shiseido as a prestigious and reliable brand.

Sigma Beauty made its name with quality, cruelty-free makeup brushes and innovative brush-cleaning tools. It later expanded into color cosmetics, with popular eyeshadow palettes and brush sets. Sigma is clean-leaning, vegan-friendly, and appreciated for durability and pro-level precision.

Sisley Paris is a luxury French brand known for blending advanced science with high concentrations of botanical extracts. Hero products like the Black Rose Cream Mask deliver spa-like results with a sensorial experience. While not certified clean, Sisley focuses on naturally derived ingredients and has taken steps toward sustainability through responsible sourcing and eco-packaging. Consumers appreciate its efficacy and elegance, though the price point positions it firmly in the prestige category.

Skin&Co Roma blends Italian heritage and farm-sourced ingredients like truffle extract to create quality skincare. The Truffle Therapy line is their hero collection, offering antioxidant-rich, nourishing formulas. Cruelty-free and clean-leaning, the brand marries old-world botanicals with modern skincare.

Skin Inc combines customization and tech, offering personalized skincare serums based on skin needs. Known for their My Daily Dose serums and Optimizer Voyage Tri-Light LED device, the brand focuses on minimalism and efficacy. Clean, cruelty-free, and loved for a tech-meets-skincare approach.

SkinCeuticals is a medical-grade skincare brand rooted in skin cancer research, highly recommended by professionals for high-potency, antioxidant-rich formulas. Their CE Ferulic is iconic, revered by consumers seeking serious, clinically proven results for skin health.

SkinMedica is a dermatologist-developed brand recognized for its advanced anti-aging treatments, especially the TNS Advanced+ Serum, featuring growth factors. Not a clean brand, but backed by science and trusted by professionals for results-driven, medical-grade formulations.

Skinbetter Science is a physician-dispensed brand known for its advanced, science-backed anti-aging skincare with patented technologies. While not broadly "clean" certified, it focuses on clinically proven ingredients like those in Alto Advanced Defense and Repair Serum, earning a premium reputation for visible results.

Dedicated to barrier health, SkinFix offers clinically proven skincare for dry, sensitive, and eczema-prone skin. This "cleanical" brand, certified by unbiased dermatologists, crafts formulas free of common irritants. Their Barrier+ Lipid-Peptide Cream and Eczema+ Hand Repair Cream are highly acclaimed. Consumers, especially those with sensitive skin, show strong sentiment for their genuinely effective, clean, and clinically sound formulations.

Smashbox is a photo studio-born makeup brand known for performance under flash and camera, with its cult-favorite Photo Finish Primer anchoring the line. While it doesn’t fall under the clean beauty category, Smashbox is cruelty-free and has made strides toward more sustainable packaging. Now under Estée Lauder, it enjoys steady loyalty from makeup lovers who value long-wear, pro-level products.

Smith & Cult originally launched as a luxe nail polish brand known for its edgy packaging and high-performance formulas. It expanded into color cosmetics with bold lip and eye products, emphasizing creative expression. Cruelty-free and glam-forward, it’s known for its cool-girl aesthetic and artistry appeal.

Sol de Janeiro embodies the joyful spirit of Brazil, offering body care and fragrances known for their delicious scents and indulgent textures. They champion a "clean philosophy," being cruelty-free, vegan and free of many questionable ingredients. Their Brazilian Bum Bum Cream and Cheirosa '62 Fragrance Mist are immensely popular. Consumer sentiment is overwhelmingly positive, driven by the sensory experience and effective products.

Sonäge is a spa-grade skincare brand with French roots, blending botanicals and science for a "New Natural" approach. EWG Verified and committed to eco-friendly packaging, they offer luxurious yet conscious products for effective results and self-care.

St. Tropez is a fan-favorite self-tanning brand offering a wide range of bronzing mousses, mists, and gradual tanners. Its Self Tan Express formula is especially popular for customizable color. St. Tropez is synonymous with sunless glow and natural-looking tans.

Stratia is a science-backed indie skincare brand focused on barrier repair and minimalism, created by skincare blogger Alli Reed. Known for Liquid Gold, a cult-favorite ceramide-rich moisturizer, Stratia formulates with transparency and a strong evidence base. All products are cruelty-free and free of unnecessary fillers, aligning closely with clean beauty values, though not officially certified. Consumers appreciate the brand's honesty, affordability, and effectiveness.

StriVectin is a science-driven skincare brand focusing on anti-aging and skin health, powered by their patented NIA-114™ technology. They emphasize clinical validation and visible results for concerns like wrinkles and neck lines. Their Neck Cream is a best-seller, and their innovative formulas have earned numerous awards. Consumers typically choose StriVectin for its targeted, results-oriented approach to mature skin concerns.

A luxury Korean skincare brand, Sulwhasoo deeply integrates traditional Korean herbal medicine (Hanbang) with modern science, particularly focusing on ginseng. Their First Care Activating Serum and Concentrated Ginseng Renewing Cream are highly celebrated. Consumer sentiment values their unique heritage, potent ingredients, and luxurious experience.

Summer Fridays offers clean, Instagram-friendly skincare like the Jet Lag Mask, rooted in simplicity, vegan formulations, and sustainable packaging efforts.

Sunday Riley is a "green technology" skincare brand blending advanced, clinically proven ingredients with botanicals for fast-acting, non-irritating formulas. They prioritize clean formulations and green lab practices, with popular products like Good Genes lauded for their visible results and sophisticated approach.

Supergoop! is a sun-care brand dedicated to making SPF a daily, enjoyable part of everyone's routine. Their unique offerings include innovative, lightweight, and broad-spectrum SPF formulas designed for everyday wear, often blending skincare benefits. Best-selling products include Unseen Sunscreen and Glowscreen.